You recognize the name on the badge before you consciously register the face — someone whose work you've followed for years, suddenly three feet away at a coffee station instead of a byline on a paper. The nerve required to walk over gets most of the attention in advice about this moment, and it's real, but it's not actually where most attempts go wrong. What sinks a good opening is the ask itself: vague enough that saying yes costs the other person more thought than they have time for between sessions, so the easiest answer is a polite non-answer that goes nowhere.

“Can I pick your brain” asks for nothing and gets nothing

The vague version of this request is everywhere because it feels lower-risk to say — it commits the asker to nothing specific and leaves an easy exit if the answer is no. It also gives the other person nothing to say yes to. “Pick your brain about what, exactly, for how long, starting when?” is the honest translation a busy senior attendee hears, even if they're too polite to say it out loud, and the default response to an open-ended request between sessions is a friendly “sure, let's try to connect” that both of you know isn't going to happen. Specificity does the opposite work: it turns an abstract imposition on someone's time into a concrete, boundaried favor that's easy to actually grant.

Make the yes a single word

Propose the logistics yourself rather than asking the other person to solve a scheduling problem on your behalf. “I have one specific question about X — do you have fifteen minutes after this session, or at the coffee break tomorrow morning? I'll find you” gives a genuinely busy person a decision they can make in the time it takes to read the sentence: yes, no, or a different time that suits them better. The version that asks “when would be good for you?” hands back exactly the scheduling work you were trying to save them from, and a request that creates more work than it promises value gets deprioritized every time, politely, the same way an open-ended networking ask gets deprioritized against the sessions someone already committed to attending.

Bring one real question, not a pitch

The fifteen minutes you asked for is worth almost nothing if you spend it on a summary of your own background hoping something in it prompts advice, or worse, an unannounced pitch dressed up as a question. Bring the single sharpest open question you actually have — something specific enough to their experience that only they, or someone with their exact history, could answer it usefully. A good test before you ask it: would a generic answer from anyone in the field satisfy you, or does the value specifically depend on this person's own path? If the honest answer is the former, the question belongs to the hallway track generally, not to fifteen minutes you asked a stranger to carve out of their day.

The follow-up is one email, once

Send a short thank-you within a day or two — specific about what was useful, not a generic “great meeting you” — and let that be the close of the loop unless they explicitly invite more contact. The mistake that undoes an otherwise well-run fifteen minutes is treating the granted meeting as the opening of an ongoing relationship rather than the complete, generous thing it already was; a second ask a month later, with no new specific reason, reads as exactly the imposition the first request worked hard not to be. If the conversation genuinely earned a next step — they offered to make an introduction, or asked to see something you mentioned — follow up on that concrete thread and nothing broader. The same restraint that made the ask easy to grant is what keeps the door open for a second one, someday, at a different conference.

Worth a look in the directory

  1. RAPS Convergence 2026 — a flagship week large enough that senior figures across the whole profession are genuinely reachable
  2. DIA Real-World Evidence Conference 2026 — a smaller, single-track program where the same senior person turns up at every coffee break

More from Save the Date

  1. Networking for people who hate networking
  2. The colleague you send
  3. How to work a regulatory conference

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